Postdoctoral Researcher in translational biomedicine

The Kaukonen research group at the Department of Medical and Clinical Genetics at the Faculty of Medicine, University of Helsinki invites applications for the position of a POSTDOCTORAL RESEARCHER for a fixed-term position of 12 months with possibility to extension (starting date negotiable). Our research group develops novel therapies for inherited retinal diseases (IRDs), combining human genetics, gene therapy, CRISPR-based gene editing, stem cell technologies, and translational disease modelling. We are particularly interested in developing treatments for retinal disorders prevalent in the Finnish population and advancing promising therapeutic strategies toward clinical application. The group collaborates extensively with national and international partners. Our work spans patient-derived cell models, retinal organoids, and animal models, creating a unique translational pipeline from gene discovery to therapy development. The successful candidate will join a growing research programme focused on: Developing gene therapy approaches for inherited retinal diseases. Designing and optimising CRISPR-based gene editing strategies, including base editing and prime editing. Generating and characterising patient-derived induced pluripotent stem cell (iPSC) models and retinal organoids. Evaluating therapeutic efficacy using molecular, cellular and functional assays. Contributing to translational studies that support future clinical development of retinal therapies.

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